April 19, 2024

Does Meloxicam Cause Weight Gain?

Introduction: Does Meloxicam Cause Weight Gain?

Meloxicam is a nonsteroidal anti-inflammatory drug (NSAID) commonly prescribed to alleviate pain, inflammation, and stiffness associated with conditions like osteoarthritis and rheumatoid arthritis. While effective in providing relief from these symptoms, concerns have been raised regarding its potential impact on weight gain. In this article, we will explore the relationship between meloxicam usage and weight gain to gain a deeper understanding of this topic.

Understanding Meloxicam

Before discussing the potential effects of meloxicam on weight, it is essential to briefly understand what meloxicam is and how it works. Meloxicam belongs to a class of medications called NSAIDs, which work by reducing the production of prostaglandins, substances responsible for pain, inflammation, and swelling. This action helps alleviate pain and inflammation, enabling individuals to manage their conditions more comfortably.

Meloxicam and Weight Gain: Fact or Fiction?

The association between meloxicam usage and weight gain has been a matter of concern among patients and healthcare providers. While meloxicam is not known to directly cause weight gain, it is important to consider certain factors that may contribute to weight fluctuations or changes in body composition:

  1. Fluid Retention: NSAIDs can sometimes lead to fluid retention, causing temporary weight gain. This occurs as a result of altered sodium balance in the body. While fluid retention is not actual weight gain (fat accumulation), it can make individuals feel heavier and cause changes in the number displayed on the scale.
  2. Appetite Changes: Pain and inflammation associated with conditions like arthritis can sometimes affect appetite. In some cases, meloxicam may help relieve pain and improve overall well-being, leading to increased appetite and potential weight gain. However, it is important to note that changes in appetite are subjective and can vary from person to person.
  3. Individual Metabolic Response: Each individual may respond differently to meloxicam, with variations in how the drug affects their metabolic processes. While some individuals may experience increased appetite and potential weight gain when using meloxicam, others may not observe any significant changes in their weight or body composition.

Considering the Research

While evidence specifically linking meloxicam usage to weight gain is limited, it is important to acknowledge that research in this area is ongoing. Different studies may present varying results due to factors such as dosage, treatment duration, individual response, and the presence of underlying medical conditions.

In a study published in the journal Pharmacoepidemiology and Drug Safety, researchers analyzed data from a large population-based study and found no significant association between meloxicam use and weight gain in individuals with osteoarthritis. This suggests that meloxicam is unlikely to be a significant contributor to weight gain in this population. However, it is important to note that individual responses may vary, and potential weight changes can be influenced by multiple factors.

Managing Weight while Using Meloxicam

If you are concerned about potential weight gain while using meloxicam, consider the following recommendations to help manage your weight effectively:

  • Maintain a Balanced Diet: Focus on consuming a well-balanced diet that includes plenty of fruits, vegetables, whole grains, lean proteins, and healthy fats. Avoid excessive consumption of processed foods, sugary snacks, and beverages, as they can contribute to weight gain.
  • Regular Exercise Routine: Engage in regular physical activity based on your abilities and medical advice. Incorporating exercises such as walking, swimming, or cycling can help maintain a healthy weight, improve overall well-being, and manage joint-related symptoms.
  • Stay Hydrated: Drinking an adequate amount of water throughout the day is essential for overall health and can help minimize fluid retention. Proper hydration supports various bodily functions and may help mitigate potential bloating or discomfort caused by fluid retention.
  • Communicate with Healthcare Provider: If you have concerns about weight gain or changes in body composition while using meloxicam, it is important to discuss these issues with your healthcare provider. They can evaluate your specific situation, consider alternative treatment options, or provide additional guidance on managing your weight alongside meloxicam usage.


While meloxicam is not known to directly cause weight gain, potential factors such as fluid retention and changes in appetite may contribute to weight fluctuations or perceived weight gain. It is important to remember that individual responses to medications can vary, and factors beyond meloxicam usage, such as underlying health conditions and lifestyle choices, can also influence weight changes.

If you have concerns about weight gain while using meloxicam, it is advisable to consult with your healthcare provider. They can provide personalized guidance and support based on your specific circumstances and help you manage your health effectively. Additionally, adopting a balanced diet, regular physical activity, and maintaining open communication with your healthcare provider will contribute to promoting overall well-being while managing your condition.

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